Frame Therapeutics is dedicated to transforming the treatment of cancer by directing the immune system towards Frame neoantigens. This is done by personalized cancer vaccines, available off-the-shelf, anywhere in the world.
Our technology is based on the combination of two recent breakthrough developments in genomics and immunotherapy. First, next-generation DNA sequencing technology makes it possible to rapidly read the genomes of both tumor and healthy cells and identify mutations that may give rise to neoantigens. This gives the opportunity to create personalized medicines that are based on the tumor DNA sequence of the patients.
Second, new developments in immunology have made immunotherapy of cancer a new treatment option, in addition to the three classic pillars of oncological treatment: surgery, radiation and chemotherapy. Analysis of mutations across thousands of tumors helped us identify the best neoantigens to include in vaccines which can be prepared and stored on the shelf and made available for patients and their doctors on demand.
In this way, we create a personalized therapy for each patient, instead of a generic drug. It is available off-the-shelf when the patients need it. Patients don’t have time to lose.
At Frame Therapy, we are committed to progressing the field of immunotherapy, with a goal to eradicate cancer by initially developing personalized, off-the shelf anti-cancer vaccines that focus on the unique and individual nature of a patient’s tumor. Our dynamic team combines novel science with focus on team work, and we are looking for passionate, innovative people to join us.